@thesis{kamalakannan_development_2023, title = {Development of a time-of-flight mass spectrometer with a laser desorption-ionization ion source for {SMILES} (Séparation en Masse couplée à l’Ionisation Laser pour des applications Environnementales et en Santé) project}, url = {https://theses.hal.science/tel-05293795}, abstract = {The {SMILES} (Séparation en Masse couplée à l’Ionisation Laser pour des applications Environnementales et en Santé) mass separator is currently in development at the {SUBATECH} laboratory. It aims to analyze isotopes for environmental and medical purposes, using laser ionization. Two types of mass separators will be built: one with a dipole magnet and a hot cavity ion source, and the other, a Time-of-Flight Mass Spectrometer ({TOF}-{MS}) with a laser desorption- ionization ({LDI}) source. This thesis focuses on developing a {TOF}-{MS}, mainly for analyzing environmental contaminants. {TOF}-{MS} differentiates elements based on their time of flight, proportional to √��/�� ratio. A {TOF}-reflectron ({TOF}-R) will be developed for the {SMILES} project, with a linear {TOF} ({TOF}-L) serving as a pilot prototype. {SIMION} software assists in studying ion trajectories in electric and magnetic fields during the design process.}, institution = {Nantes Université}, type = {phdthesis}, author = {Kamalakannan, Keerthana}, urldate = {2025-10-09}, date = {2023-12-12}, langid = {english}, keywords = {thesis}, }