@phdthesis{kamalakannan_development_2023, type = {phdthesis}, title = {Development of a time-of-flight mass spectrometer with a laser desorption-ionization ion source for {SMILES} ({Séparation} en {Masse} couplée à l’{Ionisation} {Laser} pour des applications {Environnementales} et en {Santé}) project}, url = {https://theses.hal.science/tel-05293795}, abstract = {The SMILES (Séparation en Masse couplée à l’Ionisation Laser pour des applications Environnementales et en Santé) mass separator is currently in development at the SUBATECH laboratory. It aims to analyze isotopes for environmental and medical purposes, using laser ionization. Two types of mass separators will be built: one with a dipole magnet and a hot cavity ion source, and the other, a Time-of-Flight Mass Spectrometer (TOF-MS) with a laser desorption- ionization (LDI) source. This thesis focuses on developing a TOF-MS, mainly for analyzing environmental contaminants. TOF-MS differentiates elements based on their time of flight, proportional to √��/�� ratio. A TOF-reflectron (TOF-R) will be developed for the SMILES project, with a linear TOF (TOF-L) serving as a pilot prototype. SIMION software assists in studying ion trajectories in electric and magnetic fields during the design process.}, language = {en}, urldate = {2025-10-09}, school = {Nantes Université}, author = {Kamalakannan, Keerthana}, month = dec, year = {2023}, keywords = {thesis}, }