%0 Thesis
%T Development of enriched gadolinium target for cross section measurement and future production of terbium for nuclear medicine
%I Nantes Université
%R phdthesis
%U https://theses.hal.science/tel-04047001
%X Radionuclides of terbium have attracted much attention for their potential applications in nuclear medicine. However, the short supply of terbium isotopes has limited their applications. This work proposes to use enriched gadolinium targets to produce terbium radioisotopes in biomedical cyclotrons via light-particle-induced reactions. The Auger and gamma emitter 155Tb is taken as a study case using the reaction 155Gd(d,2n)155Tb. To estimate the production yield, thin Gd- containing targets have been firstly developped to measure the cross sections. To this end, the co-electrodeposition method has been chosen to manufacture Ni-Gd2O3 composite targets. Several process parameters that have an impact on deposit quality are stutied to increase the Gd content (up to 3 mg in the deposit). The cross section measurement of natGd(d,2n)Tb, as a proof-of-conception experiment, has been carried out at GIP ARRONAX cyclotron facility using natural Ni-Gd2O3 targets. The production yield is estimated using these results. Thick targets have also been developped via pelletizing method for mass production. The optimal experimental conditions and pellet properties under these conditions have been investigated. An enriched 155Gd2O3 target was irradiated with an incident energy of 15 MeV. The production yield of 155Tb was found to be 10 MBq/μAh and the purity was 89%, which are consistent with the estimation. The coproduction of other Tb isotopes and the recycle of Gd are also involved in this thesis.
%G en
%A Wang, Yizheng
%D 2022-12-06
%K thesis