In solution Cu-67 is usually in divalent state. It can be radiolabelled with macrocyclic chelators. DOTA is being used, but other, specific copper chelators such as MeCOSar may provide improved stability.
Cu-67 decays by β- decay with a half-life of 2.576(5) days to stable Zn-67. It emits a low energy β- spectrum with 145 keV average energy and 561 keV maximum energy based on branching ratios measured in . In addition to β- emission it also emits low energy conversion and Auger electrons , thus emitting in total about 1.2 electrons (with energies above 7 keV) per decay.
The radiochemical separation is performed at ARRONAX (Nantes, France) and activity will be shipped from there to the users in form of CuCl2 solution.
Examples of use
|Daughter||Decays to stable Zn-67: 100% β-|
|Processing||2-step column separation|
|Primary Container||2.5 mL borosilicate glass V-vial with silicon rubber screw cap|
|Physical Form||Liquid or solid deposit|
|Chemical Form||In 0.1 M HCl (evaporation to dryness is also possible)|
|Radioactive Concentration (gamma spectrometry)||n.a.|
|Appearance||Clear colourless solution|
|Radionuclide identification (gamma spectrometry)||185 keV gamma line present|
|Radionuclidic Purity (gamma spectrometry)||Not yet defined|
|Chemical purity (ICP-OES)||n.a.|
|Molar activity (ICP-OES)||n.a.|
|Apparent Molar Activity||n.a.|
|pH (pH strips)||Depends on chemical form|
|Activity available||200 MBq per batch (planning in advance)|
|Activity limit for UN2910 (excepted package) shipment||0.7 GBq in dry state or 70 MBq in liquid form|